Managing IOP Response

“If the patient is not responding sufficiently to your current therapy, you owe it to them to treat the edema and trust either yourself or your colleagues to manage the rest, if needed.”

— John W. Kitchens, MD

Results presented below are from a single case; results may vary.

John W. Kitchens, MD

Dr. Kitchens is a partner and practicing retinal specialist at Retina Associates of Kentucky, the largest retina-only practice in the state. He has been voted one of the Best Doctors in America and one of America’s Top Ophthalmologists.

Academic affiliations:

  • Received his MD from the Indiana University School of Medicine
  • Completed his ophthalmology residency at the University of Iowa Hospitals and Clinics Eye and Ear Infirmary followed by a vitreoretinal fellowship at the University of Chicago Department of Ophthalmology and Visual Sciences
  • Was chief resident at Bascom Palmer Eye Institute in Miami, Florida, where he also completed his retinal fellowship

Patient profile1

Sex: Male
Age: 64
Diagnosis: DME
Treated eye: OD
Concomitant conditions: Poorly controlled type 2 diabetes mellitus
Treatment history:
• 1X Focal laser
• 30X Anti-VEGF
• 11X Corticosteroid
Notes: Pseudophakic

Reasons Dr. Kitchens chose ILUVIEN:

  • Patient experienced a gradual waning of response to anti-VEGF therapy
  • Patient concern with frequent injections
  • Prior IOP elevation with corticosteroid therapy was managed effectively with topical drops and considered not clinically significant
  • Desire to provide the patient with a long-lasting treatment

Patient outcome

  • Sustained visual acuity and reduction in retinal thickness for 14 months with just one additional anti-VEGF injection
  • With ongoing topical therapy, no clinically significant rise in IOP has been observed
  • Improvement was seen in both visual acuity and retinal edema

“For this patient, I decided that ILUVIEN was the best course of therapy, despite his history of an IOP response. I pretreated him with drops and things seem to be going really well.”

— John W. Kitchens, MD

Retinal thickness (μm)

Best corrected visual acuity (BCVA)

Intraocular pressure (IOP)

*Patient started IOP drops after first IV steroid treatment and remains on therapy

Selected OCT Scans


ILUVIEN injected
Visual Acuity: 20/70
Letters: 55
OCT: 491 μm
IOP: 14 mm Hg


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Real-world IOP DATA
Real-world IOP DATA

Review real-world IOP data from the USER Study.